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Aspirin
Bamlanivimab
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Casirivimab/i..
Colchicine
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Fluvoxamine
Hydroxychlor..
Iota-carragee..
Ivermectin
Melatonin
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Molnupiravir
N-acetylcys..
Nigella Sativa
Nitazoxanide
Paxlovid
Povidone-Iod..
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Home   COVID-19 treatment studies  COVID-19 treatment studies  COVID-19 studies   Select treatmentSelect treatmentTreatmentsTreatments
Antiandrogens (meta) Metformin (meta)
Aspirin (meta) Molnupiravir (meta)
Bamlanivimab (meta) N-acetylcys.. (meta)
Bromhexine (meta) Nigella Sativa (meta)
Budesonide (meta) Nitazoxanide (meta)
Casirivimab/i.. (meta) Paxlovid (meta)
Colchicine (meta) Povidone-Iod.. (meta)
Conv. Plasma (meta) Probiotics (meta)
Curcumin (meta) Proxalutamide (meta)
Ensovibep (meta) Quercetin (meta)
Favipiravir (meta) Remdesivir (meta)
Fluvoxamine (meta) Sotrovimab (meta)
Hydroxychlor.. (meta) Vitamin A (meta)
Iota-carragee.. (meta) Vitamin C (meta)
Ivermectin (meta) Vitamin D (meta)
Melatonin (meta) Zinc (meta)

Other Treatments Global Adoption
Global adoption of COVID-19 early treatments
Treatment
Improvement
  (early)
Studies
  (early)
EVEnsovibep 89% 1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SSotrovimab 89% 1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NSNigella Sativa 84% 3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PLPaxlovid 83% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BUBudesonide 82% 1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
V.DVitamin D 81% 6
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BHBromhexine 79% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
V.AVitamin A 79% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
QQuercetin 79% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
BLBamlanivimab 79% 6
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
MTMelatonin 78% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
RDRemdesivir 76% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ZnZinc 74% 3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PXProxalutamide 73% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CCCurcumin 71% 6
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PIPovidone-Iod.. 71% 7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
AAAntiandrogen 68% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
IVMIvermectin 66% 30
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(H)CQHydroxychlor.. 64% 34
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FVFluvoxamine 64% 3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CICasirivimab/i.. 63% 9
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
MPMolnupiravir 55% 5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NZNitazoxanide 49% 5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FPVFavipiravir 45% 6
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
V.CVitamin C 43% 3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PBProbiotics 34% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
NACN-acetylcys.. 21% 2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
COColchicine - 0
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
AAspirin - 0
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CPConv. Plasma -93% 3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Global adoption of early treatments. Studies, improvement, and adoption refer to early treatment only. Countries ordered by population. Official:
 
  Unofficial:
 
References
Algeria
(Hydroxy)chloroquine - official - country-wide adoption
Argentina
Ivermectin - unofficial - mixed usage - Jan 26, 2021
Australia
Sotrovimab - official - country-wide adoption
Budesonide - official - country-wide adoption
Remdesivir - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Bahrain
(Hydroxy)chloroquine - official - country-wide adoption
Bangladesh
Ivermectin - official - country-wide adoption
Belarus
(Hydroxy)chloroquine - unofficial - mixed usage
Belize
Ivermectin - official - country-wide adoption - used for serious cases - Dec 18, 2020
Benin
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Bolivia
Ivermectin - official - country-wide adoption
Botswana
Ivermectin - unofficial - mixed usage
Brazil
Ivermectin - unofficial - used in some regions - Jan 26, 2021
Bulgaria
Ivermectin - official - country-wide adoption
Burkina Faso
(Hydroxy)chloroquine - official - country-wide adoption
Burundi
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Cambodia
Ivermectin - official - country-wide adoption
Cameroon
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Canada
Sotrovimab - official - country-wide adoption
Paxlovid - official - country-wide adoption
Budesonide - official - isolated use
Bamlanivimab - official - country-wide adoption
Fluvoxamine - official - isolated use
Casirivimab/imdevimab - official - country-wide adoption
Central African Republic
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Chad
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Chile
(Hydroxy)chloroquine - unofficial - mixed usage
China
(Hydroxy)chloroquine - official - country-wide adoption - CQ is used instead of HCQ
http://rs.yiigle.com/CN101723202101/1317749.htm (Internet Archive)
https://www.chinalawtranslate.com/en/coronavirus-treatment-plan-7/ (Internet Archive)
http://rs.yiigle.com/yufabiao/1246637.htm (Internet Archive)
https://www.archyde.com/china-approves-chloroquine-instead-of-hydroxychloroquine-against-c.. (Internet Archive)
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Probiotics - official - country-wide adoption
Convalescent Plasma - official - country-wide adoption
Colombia
Ivermectin - unofficial - used in many regions
Congo
Remdesivir - official - country-wide adoption
(Hydroxy)chloroquine - official - country-wide adoption
Costa Rica
(Hydroxy)chloroquine - official - country-wide adoption
Cuba
(Hydroxy)chloroquine - official - country-wide adoption
Czech Republic
Ivermectin - official - isolated use - authorized, but reportedly almost no use
(Hydroxy)chloroquine - official - country-wide adoption
Democratic Republic of Congo
(Hydroxy)chloroquine - official - country-wide adoption
Djibouti
(Hydroxy)chloroquine - official - country-wide adoption
Dominican Republic
Ivermectin - official - country-wide adoption - Sep 30, 2020
Ecuador
(Hydroxy)chloroquine - unofficial - mixed usage
Egypt
Remdesivir - official - country-wide adoption - Nov 30, 2020
Zinc - official - country-wide adoption - Nov 30, 2020
Ivermectin - official - country-wide adoption - Nov 30, 2020
(Hydroxy)chloroquine - official - country-wide adoption - Nov 30, 2020
Favipiravir - official - country-wide adoption - Nov 30, 2020
Vitamin C - official - country-wide adoption - Nov 30, 2020
El Salvador
Ivermectin - official - country-wide adoption
(Hydroxy)chloroquine - unofficial - mixed usage
Eritrea
(Hydroxy)chloroquine - official - country-wide adoption
Gabon
(Hydroxy)chloroquine - official - country-wide adoption
Germany
Budesonide - unofficial - used in some regions
Ivermectin - unofficial - isolated use - Dec 31, 2020
(Hydroxy)chloroquine - unofficial - mixed usage
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Fluvoxamine - unofficial - used in some regions
Ghana
Remdesivir - official - country-wide adoption
(Hydroxy)chloroquine - official - country-wide adoption
Greece
(Hydroxy)chloroquine - official - country-wide adoption
Guatemala
Ivermectin - official - country-wide adoption - Jan 23, 2021
Guinea
(Hydroxy)chloroquine - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Guinea-Bissau
(Hydroxy)chloroquine - official - country-wide adoption
Honduras
Zinc - official - country-wide adoption
Ivermectin - official - country-wide adoption - Apr 23, 2020
(Hydroxy)chloroquine - official - country-wide adoption
Colchicine - official - country-wide adoption
Iceland
(Hydroxy)chloroquine - unofficial - mixed usage
India
Sotrovimab - official - country-wide adoption
Budesonide - official - country-wide adoption
Remdesivir - official - isolated use
Ivermectin - unofficial - used in many regions
(Hydroxy)chloroquine - unofficial - mixed usage
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Favipiravir - unofficial - isolated use
Indonesia
Ivermectin - official - mixed usage
(Hydroxy)chloroquine - official - mixed usage
Iran
Ivermectin - unofficial - mixed usage - now manufacturing their own ivermectin, but the level of usage is unclear
(Hydroxy)chloroquine - official - country-wide adoption
Israel
(Hydroxy)chloroquine - unofficial - mixed usage
Jamaica
Ivermectin - official - isolated use - authorized for off-label use, availability delayed
Japan
Sotrovimab - official - country-wide adoption
Ivermectin - unofficial - used in some regions - May 18, 2020
Casirivimab/imdevimab - official - country-wide adoption
Lebanon
Ivermectin - official - country-wide adoption - Jan 27, 2021
Luxembourg
(Hydroxy)chloroquine - unofficial - mixed usage
Madagascar
(Hydroxy)chloroquine - official - country-wide adoption
Malaysia
Ivermectin - unofficial - isolated use
(Hydroxy)chloroquine - unofficial - mixed usage
Favipiravir - official - country-wide adoption
Mali
(Hydroxy)chloroquine - official - country-wide adoption
Mexico
Ivermectin - official - mixed usage - Dec 29, 2020
Morocco
(Hydroxy)chloroquine - official - country-wide adoption
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Namibia
Remdesivir - official - country-wide adoption
New Zealand
Budesonide - official - country-wide adoption
Nicaragua
Ivermectin - official - country-wide adoption - Jan 25, 2021
Niger
(Hydroxy)chloroquine - official - country-wide adoption
Nigeria
Ivermectin - unofficial - used in many regions
(Hydroxy)chloroquine - official - country-wide adoption
North Macedonia
Ivermectin - official - mixed usage - Jan 15, 2021
Oman
(Hydroxy)chloroquine - unofficial - mixed usage
Pakistan
(Hydroxy)chloroquine - unofficial - mixed usage
Panama
Ivermectin - official - country-wide adoption
(Hydroxy)chloroquine - unofficial - mixed usage
Paraguay
Proxalutamide - official - country-wide adoption
Ivermectin - official - used in some regions
Peru
Ivermectin - unofficial - used in some regions - was widely used but later restricted, a study shows 14x reduction in excess deaths when used and 13x increase when restricted - May 8, 2020
Philippines
Ivermectin - unofficial - isolated use
Poland
Budesonide - official - country-wide adoption - Apr 26, 2021
Remdesivir - official - country-wide adoption
Portugal
Ivermectin - unofficial - used in some regions
(Hydroxy)chloroquine - unofficial - mixed usage
Qatar
(Hydroxy)chloroquine - official - country-wide adoption
Romania
Favipiravir - official - country-wide adoption
Russia
Budesonide - official - country-wide adoption
Favipiravir - official - country-wide adoption
Saudi Arabia
Sotrovimab - official - country-wide adoption
Budesonide - official - country-wide adoption
(Hydroxy)chloroquine - unofficial - mixed usage
Casirivimab/imdevimab - official - country-wide adoption
Favipiravir - official - country-wide adoption
Senegal
(Hydroxy)chloroquine - official - country-wide adoption
Singapore
Sotrovimab - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Slovakia
Ivermectin - official - mixed usage - while approved, press has been divided, censorship is common, and access is limited but improving - Jan 27, 2021
South Africa
Ivermectin - unofficial - mixed usage - may be prescribed without section 21 approval from 3/17/21, compounding allowed from 4/7/21 - Jan 27, 2021
South Korea
(Hydroxy)chloroquine - official - country-wide adoption
Thailand
Ivermectin - unofficial - isolated use
Favipiravir - official - country-wide adoption
Tunisia
(Hydroxy)chloroquine - unofficial - mixed usage
Turkey
(Hydroxy)chloroquine - official - country-wide adoption
Favipiravir - official - country-wide adoption
USA
Sotrovimab - official - country-wide adoption
Paxlovid - official - country-wide adoption
Bamlanivimab - official - country-wide adoption
Remdesivir - official - country-wide adoption
Ivermectin - unofficial - used in some regions - Oct 31, 2020
Fluvoxamine - unofficial - isolated use
Casirivimab/imdevimab - official - country-wide adoption
Ukraine
Vitamin D - official - mixed usage
Quercetin - official - mixed usage
Melatonin - official - mixed usage
Zinc - official - mixed usage
Ivermectin - official - mixed usage
Vitamin C - official - mixed usage
Aspirin - official - mixed usage
United Arab Emirates
Sotrovimab - official - country-wide adoption
(Hydroxy)chloroquine - official - country-wide adoption
Favipiravir - official - country-wide adoption
United Kingdom
Sotrovimab - official - country-wide adoption
Budesonide - official - country-wide adoption
Casirivimab/imdevimab - official - country-wide adoption
Molnupiravir - official - country-wide adoption
United States
Molnupiravir - official - country-wide adoption
Venezuela
Remdesivir - official - country-wide adoption
Ivermectin - official - country-wide adoption
(Hydroxy)chloroquine - official - country-wide adoption
Favipiravir - official - country-wide adoption
Vitamin C - official - country-wide adoption
Vietnam
Molnupiravir - official - country-wide adoption
Favipiravir - official - country-wide adoption
Yemen
(Hydroxy)chloroquine - unofficial - isolated use
Zimbabwe
Ivermectin - unofficial - mixed usage - Jan 28, 2021
Please send us corrections, updates, or comments. Vaccines and treatments are both valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases mortality, morbidity, collateral damage, and the risk of endemic status. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. WCH and FLCCC provide treatment protocols.
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